Current and Previous ORWH U3 Projects

Since its inception in 2017, the ORWH U3 Administrative Supplement Program has funded research projects across geographical regions and spanning divergent diseases and conditions affecting underserved populations of women. 


U3 Featured Researcher

Ann Partridge

Ann Partridge, M.D., M.P.H.

Dana-Farber Cancer Institute

Ann Partridge, M.D., M.P.H., is Interim Chair of the Department of Medical Oncology at Dana-Farber Cancer Institute where she also serves as Director of the Adult Survivorship Program and Co-Founder and Director of the Program for Young Adults with Breast Cancer. A Professor at Harvard Medical School, Dr. Partridge also holds the Eric P. Winer, MD, Chair in Breast Cancer Research at Dana-Farber. Dr. Partridge’s ORWH-sponsored U3 administrative supplement investigates how to engage young women with breast cancer in self-monitoring and managing their concerns and symptoms outside of the clinical setting through YES (Young, Empowered and Strong), a previously piloted and refined multicomponent mobile health intervention. The goal is to enhance patient activation, reduce symptoms, and improve quality of life over a 6-month period compared to usual care. The research incorporates biomarker data to better understand the intervention’s efficacy and potency and to identify future intervention points based on biomarker changes. A conceptual model is proposed that links inflammatory gene expression with social determinants of health (such as minority race/ethnicity, sexual orientation, low socioeconomic status, high social deprivation, and geographic location) and alterations in patient outcomes over time.