Current and Previous ORWH U3 Projects
Since its inception in 2017, the ORWH U3 Administrative Supplement Program has funded research projects across geographical regions and spanning divergent diseases and conditions affecting underserved populations of women.
U3 Featured Researcher
Esteban G. Burchard, M.D., M.P.H.
University of California, San Francisco
Dr. Burchard is a professor of Pharmacy and Medicine at the University of California, San Francisco. He is also the director of the UCSF Asthma Collaboratory, a large interdisciplinary research program. In 2020, Dr. Burchard’s ORWH-sponsored U3 administrative supplement studied the relationship between pregnancy-related exposures and methylation patterns in the mother and child. His work also explored evidence for epigenetic change between generations and how this might affect childhood respiratory health outcomes associations (e.g., asthma, wheezing, and viral respiratory illness). The project used a prospective cohort of pregnant mothers and their offspring from the Puerto Rican Infant Metagenomic and Epidemiologic Study of Respiratory Outcomes (PRIMERO). This project builds on previous work that focused on pregnancy-related health complications, psychosocial stress with epigenetics, and efforts to characterize the genetic underpinnings of the relationship between early-life viral respiratory infections and later-life development of asthma.
