Sex and Gender in Health and Disease (SGHD) Scientific Interest Group (SIG)

Date and Time

– November 20, 2018, 04:00 PM EST
Sex Differences in Cardiovascular Disease

NIH Main Campus, Porter Neuroscience Building (Building 35A), Room 620/630


Elizabeth Murphy, Ph.D.
Head of the Cardiac Physiology Section, Cardiovascular Branch
National Heart, Lung, and Blood Institute (NHLBI)

Although gender disparities in cardiac disease have been recognized, the mechanisms through which pre-menopausal women are protected have not been fully explained. Since cardiac disease incidence in women increases post-menopause, estrogen may play a role in pre-menopausal cardioprotection. However, clinical trials have found no beneficial cardiovascular outcomes from hormone replacement therapy. In this talk, Dr. Murphy will address the role of estrogen in cardioprotection.


The purpose of the NIH Scientific Interest Group (SIG) on Sex and Gender in Health and Disease (SGHD) is to:

  • Explore the influences of sex (as a biological variable) and gender (as a social construct) on health and disease across the lifespan;
  • Promote the dissemination of research and foster potential interdisciplinary collaborations among NIH scientists who work on, or are interested in, aspects of sex-based research across the research continuum or in sex-differences research relevant to health and disease; and 
  • Serve as a platform for cross-disciplinary connections to inform biomedical and social and behavioral research efforts.

The SGHD SIG also aims to catalyze new collaborations by leveraging the scientific expertise and acumen at NIH and neighboring research institutions. The SIG co-chairs are Dr. Elena Gorodetsky ( and Dr. Katrina Serrano (, both in the Office of Research on Women’s Health.


Individuals with disabilities who need a sign language interpreter and/or reasonable accommodation to participate in this event should contact Ms. Dana Simms, Office of Research on Women's Health,, 301-451-7082, and/or the Federal Relay (1-800-877-8339).