The Office of Research on Women’s Health and the Office of AIDS Research, along with 17 institute, center, and office partners, issued a Notice of Special Interest (NOSI) to highlight interest in receiving intersectional HIV research and training grant applications that explicitly center the health needs of cisgender women and girls and gender-diverse people.  

According to the Joint United Nations Programme on HIV/AIDS (UNAIDS), women and girls accounted for more than half (53%; 20.7 million) of the 39 million people with HIV and 46% of new acquisitions in 2022, with approximately 4,000 adolescent girls and women acquiring HIV on a weekly basis. Worldwide HIV prevalence among transgender women is approximately 20% and transgender women experience a 14-fold higher chance of acquiring HIV (Stutterheim, 2021).

Despite tremendous scientific advances that have brought forth significant progress in confronting the HIV epidemic, women—particularly women of color, young women and girls, and transgender women— and gender-diverse individuals remain disproportionately affected by HIV. An intersectional, equity-informed, data-driven approach is essential to advancing HIV research and clinical care for all women who have been impacted by HIV across their lifespan and to end the HIV pandemic.

Applicants are strongly encouraged to discuss proposed submissions for this initiative with the scientific contact for the proposed institute or center prior to submission to ensure alignment with institute or center mission areas and priorities for this initiative.

The NOSI expires January 8, 2026. Check the individual Notice of Funding Opportunities for applicable receipt dates here.