This page includes Notices of Funding Opportunities at NIH that may be relevant to the autoimmune disease and autoimmunity research communities.

StatusTitleAnnouncement NumberDue Dates(s)Expiration Date(s)

ACTIVE

NOSI: Stimulate Research on the Diagnosis, Treatment, and Mechanistic Understanding of Postural Orthostatic Tachycardia Syndrome (POTS)

NOT-HL-24-018 

Vary by IC01/08/2028 

ACTIVE

NOSI: Understanding the Basic Mechanisms of Immune-related Adverse Events (irAEs) in Cancer Immunotherapy

NOT-CA-24-055

Vary by IC

11/6/2027

ACTIVENOSI: Women’s Health ResearchNOT-OD-24-079Vary by NIH ICs11/5/2027
ACTIVENOSI: Autoimmune Inner Ear Disease 
(Clinical Trials Not Allowed) 		NOT-DC-25-0032/16/202510/17/2027

ACTIVE

NOSI: Systems Modeling of Infection and Immunity Across Biological Scales 

NOT-AI-24-060 

Standard NIH Due Dates 

9/8/2027 

ACTIVE

Examining the Impact of Artificial Intelligence (AI) on Healthcare Safety (R18) 

PA-24-261

Standard NIH Due Dates

5/26/2027

ACTIVE

Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed) 

PAR-25-131

1/28/2025

4/16/2027 

ACTIVE

NOSI: R13 Support for Conferences and Scientific Meetings to Support Consensus Building for Autoimmune Disease Research Related Common Data Elements 

NOT-OD-24-145

4/12/2025

12/14/2026

ACTIVENOSI: Research Supplements to Promote Re-Entry, Re-integration into, and Re-training in Health-Related Research Careers (Admin Supp - Clinical Trial Not Allowed)NOT-OD-23-170Vary by NIH Institutes and Centers (ICs)10/9/2026
ACTIVENOSI: Research on the Health of Women of Underrepresented, Underserved, and 
Underreported (U3) Populations (Admin Supp Clinical Trial Optional) 		NOT-OD-24-1791/22/2025
1/22/2026		1/23/2026

ACTIVE

Time-Sensitive Research Opportunities in Environmental Health Sciences (R21 Clinical Trials Not Allowed) 

RFA-ES-25-003

2/3/2025

12/2/2025

ACTIVETowards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R21 - Clinical Trial Optional)PAR-25-1152/16/202511/17/2025
ACTIVETowards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R01 - Clinical Trial Optional)PAR-25-1162/5/202511/6/2025

ACTIVE

Exploratory/Developmental Research on Guillain Barre Syndrome (GBS) and Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) (R21 - Clinical Trial Not Allowed) 

RFA-NS-25-025

3/3/2025

10/4/2025

ACTIVE

Complement-ARIE New Approach Methodologies (NAMs) Data Hub and Coordinating Center (U24 Clinical Trial Optional) 

NOT-RM-24-013

3/10/25

3/11/25

ACTIVE

Complement-ARIE New Approach Methodologies (NAMs) Technology Development Centers (UM1 Clinical Trial Optional) 

RFA-RM-24-010

2/28/2025

3/1/2025

CLOSEDNotice of Intent to Publish a Funding Opportunity Announcement for Complement-ARIE New Approach Methodologies (NAMs) Data Hub and Coordinating Center (U24 Clinical Trial Optional) 

NOT-RM-24-015

 

Est. Publication Date of NOFO: 11/29/2024 Est. Application Due Date:
3/10/2025

CLOSED

Notice of Intent to Publish a Funding Opportunity Announcement for Complement-ARIE New Approach Methodologies (NAMs) Technology Development Centers (UM1 Clinical Trial Optional)

NOT-RM-24-012

Est. NOFO Publication Date: 10/18/2024 

Est. Application Due Date: 2/28/2025 

CLOSEDEnvironmental Health Disparities Centers (P50) Clinical Trial OptionalRFA-MD-24-01012/5/202412/6/2024
CLOSEDOrgans-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R01 Clinical Trial Not Allowed)RFA-DE-25-00111/19/202411/20/2024
CLOSEDOrgans-on-a-Chip in Dental, Oral, and Craniofacial Research (DOC-OoCs) (R21 Clinical Trial Not Allowed)RFA-DE-25-00211/19/202411/20/2024

CLOSED

HEAL Initiative: HEAL KIDS (Knowledge, Innovation and Discovery Studies): Chronic Pain Program (UC2 Clinical Trial Optional) 

RFA-AR-24-007

11/8/2024

11/9/2024

CLOSED

Notice of Intent to Publish a Funding Opportunity Announcement for Towards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R01 - Clinical Trial Optional)

NOT-NS-24-105

Est. NOFO Publication Date: 10/28/2024

Est. Application Due Date:
2/3/2025

CLOSED

Notice of Intent to Publish a Funding Opportunity Announcement for Towards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R21 - Clinical Trial Optional)

NOT-NS-24-108

Est. NOFO Publication Date: 10/28/2024

Est. Application Due Date:
2/3/2025

CLOSED

RADx® Tech ACT ENDO Challenge Advancing Cures and Therapies and ending ENDOmetriosis diagnostic delays (ACT ENDO) Challenge 

-

Phase I:
10/11/2024

-

CLOSED

RFI: Evolving the Network of the National Library of Medicine (nih.gov)

NOT-LM-24-001

8/30/2024

8/30/2024

CLOSEDRare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN) (U54 Clinical Trial Optional)PAR-24-2068/13/20248/14/2024

CLOSED

RFI: NIH Common Fund is Soliciting Ideas for NIH-wide Challenges and Opportunities 

NOT-RM-24-010

8/10/2024

8/10/2024

CLOSEDUnderstanding Chronic Conditions Understudied Among Women (R21 Clinical Trial Optional)RFA-OD-23-0136/20/20246/21/2024
CLOSEDUnderstanding Chronic Conditions Understudied Among Women (R01 Clinical Trial Optional)RFA-OD-23-0146/20/20246/21/2024
CLOSEDRFI: Proposed Use of Common Data Elements (CDEs) for NIH-Funded Clinical Research and TrialsNOT-OD-24-0634/20/20244/20/2024
CLOSEDTeam Science Leadership Scholars Program (LSP) in Women’s Health, Autoimmune and Immune-Mediated Diseases 2.0RFA-AMPAIM-LSP-23-0024/1/20244/1/2024
CLOSEDRFI: Inviting Input on an NIH-Wide Strategic Plan for Autoimmune Disease ResearchNOT-OD-24-0493/1/20243/1/2024
CLOSEDNOSI: Research on the Health of Women of Understudied, Underrepresented and Underreported (U3) Populations (Admin Supp Clinical Trial Optional)NOT-OD-24-0321/31/20242/1/2024
CLOSEDNOSI: EXposome in Autoimmune Disease Collaborating Teams PLANning Awards (EXACT-PLAN) (Clinical Trials Not Allowed) NOT-OD-23-1126/16/20236/17/2023
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