The Sex and Gender in Health and Disease (SGHD) scientific interest group (SIG) will host a virtual talk by Alberto Bosque, Ph.D., M.B.A.—Assistant Professor in the Department of Microbiology, Immunology, and Tropical Medicine at The George Washington University—titled “Using Primary Cell Model Systems to Evaluate the Role of Biological Sex in HIV Latency and Cure Strategies.” 

The webinar will look into the basic mechanisms underlying HIV latency establishment and reversal required to develop successful HIV cure interventions. Dr. Bosque will highlight his team's research and development of a primary model of latency that uses CD4 T cells isolated from HIV-negative donors. Attendees will also learn about the many current uses of the model, such as discovering and evaluating latency-reversing agents, and potential future uses for the model, such as understanding the mechanisms involved in HIV persistence in CD4 T cells.